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Full publication list:

LABORATORY OF

CELL STRESS & IMMUNITY

Top 3 flagship research publications:

Image by National Cancer Institute

Immune-biomarkers

A spatial architecture-embedding HLA signature to predict clinical response to immunotherapy in renal cell carcinoma

Nature Medicine 2024

Image by National Cancer Institute

Immuno-oncology

Targeting conserved TIM3+VISTA+ tumor-associated macrophages overcomes resistance to cancer immunotherapy

Science Advances 2024

Image by National Cancer Institute

Cancer Immunotherapy

Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+T cells

Cell Rep. Medicine 2024

Figures collage from our major research publications (click on image to go to papers):

A spatial architecture-embedding HLA signature to predict clinical response to immunotherapy in renal cell carcinoma

Targeting conserved TIM3+VISTA+ tumor-associated macrophages overcomes resistance to cancer immunotherapy

Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells

Single cell dynamics of tumor specificity vs bystander activity in CD8+ T cells define the diverse immune landscapes in colorectal cancer

Multiomics and spatial mapping characterizes human CD8+ T cell states in cancer

CD4+ helper T cells endow cDC1 with cancer-impeding functions in the human tumor micro-environment

Peripherally-driven myeloid NFkB and IFN/ISG responses predict malignancy risk, survival, and immunotherapy regime in ovarian cancer

Full publication list:

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